The most viewed posts on Haldane’s Sieve this month were:

• Assessing allele specific expression across multiple tissues from RNA-seq read data. Pirinen et al. describe a novel method for comparing levels of allele-specific expression in different tissues.
• Probabilities of Fitness Consequences for Point Mutations Across the Human Genome. Gulko et al. describe a new approach for estimating the functional relevance of mutations in the genome using patterns of polymorphism and divergence.
• Extraordinarily wide genomic impact of a selective sweep associated with the evolution of sex ratio distorter suppression. Hornett et al. measure the genomic impact of a selective sweep that converted the sex ratio of a butterfly population from a 100:1 female-biased sex ratio to a 1:1 ratio over the course of five years.
• Author post: Sharing of Very Short IBD Segments between Humans, Neandertals, and Denisovans. Povysil and Hochreiter describe their preprint on the identification of segments of ancestry shared between modern and archaic humans.
• Author post: Single haplotype assembly of the human genome from a hydatidiform mole. Karyn Meltz Steinberg describes her preprint (with co-authors) on a new assembly of the human genome.