forqs: Forward-in-time Simulation of Recombination, Quantitative Traits, and Selection

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forqs: Forward-in-time Simulation of Recombination, Quantitative Traits, and Selection
Darren Kessner, John Novembre
(Submitted on 11 Oct 2013)

forqs is a forward-in-time simulation of recombination, quantitative traits, and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations due to recombination and/or selection on polygenic quantitative traits. forqs is implemented as a command- line C++ program. Source code and binary executables for Linux, OSX, and Windows are freely available under a permissive BSD license.

1 thought on “forqs: Forward-in-time Simulation of Recombination, Quantitative Traits, and Selection”

  1. Hi Darren and John,
    Nice paper and useful method. I thought that you might want to cite Baird 1995 [here], which also simulates individuals based on tracking junctions in a hybrid zone. It’s a nice intuitive way to think about these models, and lends itself to simulation, so there might be other previous applications too.

    Graham

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