The most viewed posts on Haldane’s Sieve in April 2014 were:
- Model adequacy and the macroevolution of angiosperm functional traits. Pennell et al. develop goodness-of-fit tests for phylogenetic models of trait evolution, and show that in many cases model fit is poor.
- Flexible isoform-level differential expression analysis with Ballgown. Frazee et al. present a statistical model for testing differential expression of genes in RNA-seq data.
- LD Score Regression Distinguishes Confounding from Polygenicity in Genome-Wide Association Studies. Bulik-Sullivan et al. was one of the most viewed preprints last month, and discussion continued in the comments this month.
- Sharing of Very Short IBD Segments between Humans, Neandertals, and Denisovans. Povysil and Hochreiter identify segments of shared ancestry between modern and archaic humans.
- Genome-wide association of foraging behavior in Drosophila melanogaster fails to support large-effect alleles at the foraging gene. Turner et al. present a genome-wide association study of the foraging behavior of Drosophila.