Monoallelic methylation and allele specific expression in a social insect

Monoallelic methylation and allele specific expression in a social insect
Kate D Lee, Zoe N Lonsdale, Maria Kyriakidou, Despina Nathanael, Harindra E Amarasinghe, Eamonn B Mallon
doi: http://dx.doi.org/10.1101/022657

Abstract

Social insects are emerging models for epigenetics. Here we examine the link between monoallelic methylation and monoallelic expression in the bumblebee \textit{Bombus terrestris} using whole methylome and transcriptome analysis. We found nineteen genes displaying monoallelic methylation and expression. They were enriched for functions to do with social organisation in the social insects. These are the biological processes predicted to involve imprinting by evolutionary theory.

Advertisement

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s