An in-host model of HIV incorporating latent infection and viral mutation

An in-host model of HIV incorporating latent infection and viral mutation
Stephen Pankavich, Deborah Shutt

We construct a seven-component model of the in-host dynamics of the Human Immunodeficiency Virus Type-1 (i.e, HIV) that accounts for latent infection and the propensity of viral mutation. A dynamical analysis is conducted and a theorem is presented which characterizes the long time behavior of the model. Finally, we study the effects of an antiretroviral drug and treatment implications.

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