This month was the most active yet on Haldane’s Sieve, with over 10,000 page views and several active comment threads. The most viewed preprints were:
- Genome Sequencing Highlights Genes Under Selection and the Dynamic Early History of Dogs. Freedman et al. perform genome sequencing of several wolves and dogs, and use this data to examine gene flow and selection during the initial domestication of dog breeds.
- Reconstructing the Population Genetic History of the Caribbean. Moreno-Estrada et al. use genomic data from populations throughout the Caribbean to examine their history. They argue that there were at least two pulses of admixture with African populations, and that there is a signature of genetic drift in the European colonists that settled the area.
- Sashimi plots: Quantitative visualization of RNA sequencing read alignments. Katz et al. present a method for visualization of RNA-seq experiments from many samples. An “Our paper” post is here.
- On the accumulation of deleterious mutations during range expansions. Peischl et al. show that populations expanding into a new habitat can accumulate deleterious mutations, and argue that this may be a relevant phenomenon for understanding human variation.
- Populations in statistical genetic modelling and inference. Lawson reviews the fundamental question of how to define a “population” in “population genetics”.